Research Article
Comparative Evaluation and Measure of Accuracy of ELISAs, CLIAs, and ECLIAs for the Detection of HIV Infection among Blood Donors in China
Table 1
Blood screening laboratories of study participation and their commercially available HIV serology kits.
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a: § CLIA,† ECLIA, and other HIV serology kits are ELISAs. b: 4th: fourth-generation ELISA kits. Other HIV serology kits are third-generation ELISA kits. ELISAs: Wantai Diagnostic Kit for antibody to human immunodeficiency virus (Beijing Wantai Biological Pharmacy, Beijing, China) (Wantai), Wantai Diagnostic Kit for antibody and antigen to human immunodeficiency virus (Beijing Wantai Biological Pharmacy, Beijing, China) (Wantai (4th)), Beijing, China; KHB Diagnostic Kit for antibody to human immunodeficiency virus (Shanghai Kehua Bioengineering Co., Shanghai, China) (KHB), InTec Diagnostic Kit for antibody to human immunodeficiency virus (InTec Products, Inc., Xiamen, China) (InTec), Livzon Diagnostic Kit for antibody to human immunodeficiency virus (Zhuhai Livzon Diagnostics Inc., Zhuhai, China) (Livzon), Livzon Diagnostic Kit for antibody and antigen to human immunodeficiency virus (Zhuhai Livzon Diagnostics Inc., Zhuhai, China) (Livzon (4th)), Murex HIV Ag/Ab combination (Diasorin, Saluggia, Italy) (Murex (4th)), Bio-Rad GS HIV Combo Ag/Ab EIA (Bio-Rad, Marnes la Coquette, France) (Bio-Rad (4th)). c: blood centers (codes 1–14) were sources of study samples. d: blood centers (codes 3–18) performed HIV screening for all the samples using one or two ELISA kits. CLIA and ECLIA were conducted by NCCL. |