Review Article
Cryptococcosis in Hematopoietic Stem Cell Transplant Recipients: A Rare Presentation Warranting Recognition
Table 2
Demographic and clinical characteristics of hematopoietic stem cell transplant recipients with cryptococcosis and characteristics of the disease.
| | Characteristic | Number (%) |
| | Gender (n = 17) | | Male | 9 (52.9) | | Female | 8 (47.1) | | Primary hematologic disease (n = 16) | | Multiple myeloma | 4 (25.0) | | Acute myelogenous leukemia | 3 (18.8) | | Acute lymphoblastic leukemia | 2 (12.5) | | Peripheral T-cell lymphoma | 2 (12.5) | | Diffuse large B-cell lymphoma | 1 (6.3) | | Follicular lymphoma | 1 (6.3) | | Hodgkin’s lymphoma | 1 (6.3) | | Myelodysplastic syndrome | 1 (6.3) | | Unspecified leukemia | 1 (6.3) | | Transplant type (n = 22) | | Allogeneic | 11 (50.0) | | Autologous | 11 (50.0) | | Site of infection (n = 23) | | CNS | 12 (52.2) | | Cryptococcemia | 4 (17.4) | | Disseminated | 3 (13.0) | | Pulmonary | 2 (8.7) | | Other | 2 (8.7) | | Outcome (n = 20) | | Dead | 10 (50.0) | | Alive | 10 (50.0) | | Species (n = 21) | | Cryptococcus neoformans | 13 (61.9) | | Cryptococcus laurentii | 3 (14.3) | | Cryptococcus sp. | 2 (9.5) | | Cryptococcus adeliensis | 1 (4.8) | | Cryptococcus albidus | 1 (4.8) | | Cryptococcus terreus | 1 (4.8) | | | Median (range) | | Age (years) (n = 17) | 47 (12–74) | | Time of onset after HSCT (days) (n = 20) | 57.5 (0–1825) |
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n, number of cases with available data from the patients.
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