Prevalence of the Helicobacter pylori babA2 Gene in Children Mainly Depends on the PCR Primer Set Used

Table 2

Association between the presence of the babA2 gene determined by 823 bp, 139 bp, and 271 bp PCR primer sets and histological parameters.

	Number of specimen				Total	Mean score	value
	Histological score
	0	1	2	3
	Bacterial density
832 bp PCR primer set
Positive	1	3	31	60	95	2.58	0.015
Negative	0	13	87	84	184	2.39
139 bp PCR primer set
Positive	1	5	50	87	143	2.56	0.007
Negative	0	11	68	57	136	2.34
271 bp PCR primer set
Positive	1	12	95	114	222	2.45	0.910
Negative	0	4	23	30	57	2.46
Activity of inflammation
832 bp PCR primer set
Positive	3	39	43	10	95	1.63	0.016
Negative	8	104	66	6	184	1.38
139 bp PCR primer set
Positive	3	63	64	13	143	1.61	0.003
Negative	8	80	45	3	136	1.32
271 bp PCR primer set
Positive	7	116	88	11	222	1.46	0.366
Negative	4	27	21	5	57	1.47
Chronic inflammation
832 bp PCR primer set
Positive	0	7	76	12	95	2.05	0.902
Negative	1	15	145	23	184	2.03
139 bp PCR primer set
Positive	0	8	111	24	143	2.11	0.063
Negative	1	14	110	11	136	1.96
271 bp PCR primer set
Positive	1	17	175	29	222	2.05	0.901
Negative	0	5	46	6	57	2.02
	Atrophic changes
832 bp PCR primer set
Positive	68	27	0	0	95	0.28	0.346
Negative	137	44	3	0	184	0.27
139 bp PCR primer set
Positive	104	38	1	0	143	0.28	0.758
Negative	101	33	2	0	136	0.27
271 bp PCR primer set
Positive	158	61	3	0	222	0.30	0.191
Negative	47	10	0	0	57	0.18
Intestinal metaplasia
832 bp PCR primer set
Positive	90	5	0	0	95	0.05	0.569
Negative	177	7	0	0	184	0.04
139 bp PCR primer set
Positive	138	5	0	0	143	0.03	0.497
Negative	129	7	0	0	136	0.05
271 bp PCR primer set
Positive	214	8	0	0	222	0.04	0.257
Negative	53	4	0	0	57	0.07

Gerhard et al. [4]; Homan et al. [15]; Sheu et al. [14].