Research Article

Pneumocystis jirovecii Pneumonia in Patients with Nephrotic Syndrome: Application of Lymphocyte Subset Analysis in Predicting Clinical Outcomes

Table 1

Patient characteristics and managements.

VariablesN = 57

Age (years)48.1 ± 16.9
Sex (female)29 (50.9%)
Duration of nephrotic syndrome (months)23.7 ± 37.5
Ever-smokers10 (17.5%)
Comorbidity
Chronic respiratory disease1 (1.8%)
Hypertension30 (52.6%)
Diabetes mellitus13 (22.8%)
 Type 2 diabetes4 (7.0%)
 Steroid-induced diabetes9 (15.8%)
Heart disease7 (12.3%)
 Coronary heart disease4 (7.0%)
 Arrhythmia1 (1.8%)
 Hypertensive heart disease1 (1.8%)
 Hypothyroid heart disease1 (1.8%)
Use of immunosuppressants
Long-term corticosteroids56 (98.2%)
 Duration of corticotherapy (months)12.6 ± 18.1
Other immunosuppressive agents50 (87.7%)
Diagnosis of PCP
 PCR56 (98.2%)
 GMS8 (14.0%)
Managements
 ICU admission37 (64.9%)
 Mechanical ventilation30 (52.6%)
 CRRT9 (15.8%)
 ECMO1 (1.8%)

PCP: Pneumocystis jirovecii pneumonia, PCR: polymerase chain reaction, GMS: Grocott’s methenamine silver stain, ICU: intensive care unit, CRRT: continuous renal replacement therapy, and ECMO: extracorporeal membrane oxygenation. Data were presented as mean ± SD or numbers (%).