Research Article

MiR-155-Mediated Deregulation of GPER1 Plays an Important Role in the Gender Differences Related to Inflammatory Bowel Disease

Figure 5

MiR-155 plays a proinflammatory role, and GPER1 is anti-inflammatory during the pathogenesis of IBD. In IBD patients, the proinflammatory cytokines IL-6 and TNFα were significantly higher, and the anti-inflammatory cytokine IL-10 was significantly lower.