Research Article
Transcriptional Profile of Helicobacter pylori Virulence Genes in Patients with Gastritis and Gastric Cancer
Table 4
Frequency of H. pylori virulence genes’ cDNA in biopsy samples of gastric and gastric carcinoma patients with H. pylori infection.
| | Gene/Disease | Gastritis, H. pylori positive (N = 23) | Gastric cancer, H. pylori positive (N = 11) | H. pylori-positive samples (N = 34) (%) | P value |
| | cagA | 1 (4.3%) | 5 (45.5%) | 17.6 | 0.008 | | CagA-EPIYAC | 1 (4.3%) | 4 (36.4%) | 14.7 | 0.029 | | cagT | 17 (73.9%) | 11 (100%) | 82.4 | 0.145 | | cagY | 5 (21.7%) | 8 (72.7%) | 38.2 | 0.008 | | cagE | 0 (0.0%) | 5 (45.5%) | 14.7 | 0.002 | | vacA s1m1 | 7 (30.4%) | 5 (45.5%) | 35.3 | 0.391 | | vacA s1m2 | 16 (69.6%) | 6 (54.5%) | 64.7 | 0.391 | | SabA/B | 15 (65.2%) | 9 (81.8%) | 70.6 | 0.074 | | BabA2/B | 8 (24.8%) | 7 (63.6%) | 44.1 | 0.469 | | oipA | 20 (87%) | 11 (100%) | 91.2 | 0.535 | | AlpA/B | 17 (73.9%) | 10 (90.9%) | 79.4 | 0.552 | | HopQI/II | 9 (39.1%) | 9 (81.8%) | 42.9 | 0.074 | | IceA1/2 | 23 (100%) | 11 (100%) | 100 | 1.000 |
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