Research Article
Transcriptional Profile of Helicobacter pylori Virulence Genes in Patients with Gastritis and Gastric Cancer
Table 5
Frequency of H. pylori virulence genes’ cDNA in gastric antral biopsy samples of gastric carcinoma patients with stomach tumors in different areas.
| | Variable/Tumor area | N (GC) | Cardia (N 14) | Body (N 4) | Lesser curvature (N 6) | Antrum (N 6) | P value |
| | H. pylori infection | 11 | 3 | 1 | 3 | 4 | 0.276 | | cagA | 5 | 1 | 0 | 2 | 2 | 0.662 | | cagA-EPIYAC | 4 | 0 | 0 | 2 | 2 | 0.284 | | cagT | 11 | 3 | 1 | 3 | 4 | 0.276 | | cagY | 8 | 2 | 1 | 2 | 3 | 0.92 | | cagE | 5 | 1 | 0 | 2 | 2 | 0.662 | | vacA s1m1 | 5 | 0 | 0 | 2 | 3 | 0.260 | | vacA s1m2 | 6 | 3 | 1 | 1 | 1 | 0.260 | | SabA/B | 9 | 3 | 0 | 3 | 3 | 0.494 | | BabA2/B | 7 | 2 | 0 | 2 | 3 | 0.810 | | oipA | 11 | 3 | 1 | 3 | 4 | 0.276 | | AlpA/B | 10 | 3 | 0 | 3 | 4 | 0.024 | | HopQI/II | 9 | 2 | 0 | 3 | 4 | 0.156 | | IceA1/2 | 11 | 3 | 1 | 3 | 4 | 0.458 |
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