Transcriptional Profile of Helicobacter pylori Virulence Genes in Patients with Gastritis and Gastric Cancer

Table 6

Frequency of H. pylori virulence genes’ cDNA in gastric carcinoma biopsy samples with G1 and G2 tumor grades. All samples with G3 and G4 tumor grades were without H. pylori infection.

Variable/Tumor grade	N	G1 (N 7)	G2 (N 14)	P value
H. pylori infection	11	4 (36.36%)	7 (63.64%)	0.047
cagA	5	1 (20%)	4 (80%)	0.303
cagA-EPIYAC	4	1 (25%)	3 (75%)	0.554
cagT	11	4 (36.36%)	7 (63.64%)	0.047
cagY	8	1 (12.5%)	7 (87.5%)	0.007
cagE	5	1 (20%)	4 (80%)	0.303
vacA s1m1	5	1 (20%)	4 (80%)	0.303
vacA s1m2	6	3 (50%)	3 (50%)	0.545
SabA/B	9	3 (33.33%)	6 (66.67%)	0.856
BabA2/B	7	2 (28.57%)	5 (81.43%)	0.735
oipA	11	4 (36.36%)	7 (63.64%)	0.047
AlpA/B	10	4 (40%)	6 (60%)	0.378
HopQI/II	9	4 (44.44%)	5 (53.64%)	0.308
IceA1/2	11	4 (36.36%)	7 (63.64%)	0.047