Research Article

Noninvasive Evaluation of Liver Fibrosis in a Sample of Putative Inactive HBV Carriers in Rome, Italy

Table 4

HBV-DNA and liver stiffness in the subgroup of 66 patients during the follow-up.

CharacteristicsBasal time12 months24 monthsChange (24 months, basal time)
% change value

HBV-DNA561.80 ± 620.015200.27 ± 18666.565202.76 ± 19597.25826.1<0.001
 HBV-DNA <2000 UI/ml, n (%)66 (100%)51 (77.3%)56 (84.8%)−15.2
 HBV-DNA ≥2000 UI/ml, n (%)0 (0%)15 (22.7%)10 (15.2%)100.0
Liver stiffness (kPa)5.80 ± 2.295.66 ± 1.435.67 ± 1.62−2.2Ns
 LS < 7.5 kPa, n (%)50 (75.8%)54 (81.8%)54 (81.8%)8.0Ns
 LS ≥ 7.5 kPa, n (%)16 (24.2%)12 (18.2%)12 (18.2%)−25.0

Continuous variables are expressed as mean ± standard deviation (SD). A value <0.05 is considered significant (Wilcoxon paired test). For categorical variables, a value <0.05 is considered significant (McNemer’s test).