Genetic Determinants of Resistance among ESBL-Producing Enterobacteriaceae in Community and Hospital Settings in East, Central, and Southern Africa: A Systematic Review and Meta-Analysis of Prevalence

Table 1

Prevalence of ESBL-producing Enterobacteriaceae from human in Eastern, Central, and Southern Africa.

Number of article (s)	Country	Settings	Prevalence (%)	ESBL gene(s)	Reference
3	Central Africa Republic	Hospital	59	blaCTX-M-15	[52]
		Community	11	blaCTX-M-15, blaTEM-1, blaOXA-1, blaSHV-2a, & blaSHV-62	[33]
			4	blaCTX-M	[31]
1	Chad	Hospital	48	blaCTX-M-9, blaCTX-M-14, blaCTX-M-15, blaCTX-M-27, blaTEM-1, & blaOXA-1	[30]
1	DR Congo	Hospital	92	blaCTX-M-1	[29]
1	Ethiopia	Hospital	50	blaCTX-M-15, blaSHV, & blaTEM	[32]
1	Gabon	Hospital	45	blaCTX-M-15, blaCTX-M-8, blaCTX-M-1, & blaTEM	[43]
3	Kenya	Hospital	51	blaCTX-M-15, blaSHV-2, blaSHV-12 , blaSHV-27, blaOXA-1, & blaOXA-10	[22]
		Community	15	blaSHV, blaCTX-M, & blaTEM	[46]
		Hospital & community	27	blaSHV-5, blaSHV-12, blaSHV-52, blaCTX-M-8, blaCTX-M-14, blaCTX-M-9, blaCTX-M-15, blaCTX-M-3, blaCTX-M-1, blaTEM-12, blaTEM-125, blaTEM-50, blaTEM-78, blaTEM-109, blaTEM-152, & blaTEM-158	[42]
2	Malawi	Hospital	62	blaCTX-M	[51]
			1	blaSHV-11, blaSHV-12, blaSHV-27, blaCTX-M-15, & blaTEM-63	[45]
2	South Africa	Hospital	19	blaCTX-M-15, blaTEM-1b, blaSHV-1, & blaOXA-1	[49]
			59	blaCTX-M-3, blaCTX-M-14, blaCTX-M-15, & blaSHV-2	[44]
10	Tanzania	Community	76	blaCTX-M-15	[40]
			34	blaCTX-M-9, blaCTX-M-15, blaCTX-M-55, blaTEM-1, blaSHV-1, & blaSHV-11	[35]
		Hospital & community	24	blaCTX-M-15 & blaSHV-12	[41]
			34	blaCTX-M-14, blaCTX-M-15, blaSHV-5, & blaSHV-12	[53]
		Hospital	64	blaCTX-M-15	[39]
			14	blaCTX-M	[38]
			89	blaCTX-M-15, blaSHV-11, blaTEM-1, blaTEM-104, & blaTEM-176	[50]
			19	blaSHV-1, blaSHV-11, blaSHV-27, blaSHV-33, blaCTX-M-15, blaTEM-1B, & blaOXA-1	[36]
			22	blaSHV-12, blaSHV-28, blaCTX-M-15, & blaTEM-1	[37]
			15	blaSHV-2a, blaSHV-12, blaCTX-M-15, & blaTEM-63	[9]
1	Uganda	Hospital	23.2	blaSHV, blaCTX-M, & blaTEM	[27]
1	Zimbabwe	Hospital	14	blaCTX-M-3, blaCTX-M-14, blaCTX-M-15, blaCTX-M-27, blaTEM, & blaSHV	[34]