A Comparative Transcriptomic Analysis of Human Placental Trophoblasts in Response to Pathogenic and Probiotic Enterococcus faecalis Interaction

Table 3

DEGs classified into placenta and embryonic development of the GO biological process category.

Group	Term	Genes
Symbioflor 1 group	GO: 0001701∼in utero embryonic development	MAFG, MAFF, XRCC2, GABPA, GNA12, SPINT1, EGLN1, BCL2L1, MBNL1, ITGB1, TPM1, CITED2, HES1, NDEL1, MSX1, PSMC4, HAND1, HSF1, TEAD4, PKD1, MKL2, LOC652826 (22)
	GO: 0001890∼placenta development	VWF, PPARD, HSF1, HAND1, CCNF, PLCD3, SPINT1, HS6ST1, EGLN1, PRDX3, CITED2 (11)
	GO: 0001892∼embryonic placenta development	HSF1, HAND1, SPINT1, EGLN1, CITED2 (5)
	GO: 0060136∼embryonic process involved in female pregnancy	HSF1, CITED2 (2)
V583 group	GO: 0043009∼chordate embryonic development	GNA13, SYVN1, XRCC2, NDST1, EGLN1, BCL2L1, ITGB1, TPM1, CITED2, HSF1, PKD1, MKL2, FLVCR1, BCL10, MAFF, ADAM10, ZNF830, TGFBR2, SPINT1, MBNL1, LIG4, GAS1, CAPN2, BRCA1, HES1, DLX2, TULP3, EP300, TSC1, PSMC4, SP3, HOXB6, MNX1, TGIF1, RIPPLY1, FOXC1, APAF1, LOC652826, POFUT1 (39)
	GO: 0009792∼embryonic development ending in birth or egg hatching	Same as GO: 0043009∼chordate embryonic development (39)
	GO: 0001701∼in utero embryonic development	GNA13, XRCC2, SYVN1, EGLN1, BCL2L1, TPM1, ITGB1, CITED2, HSF1, PKD1, MKL2, FLVCR1, MAFF, ADAM10, ZNF830, SPINT1, LIG4, MBNL1, CAPN2, HES1, TULP3, PSMC4, SP3, FOXC1, LOC652826 (25)
	GO: 0001890∼placenta development	VWF, PPARD, CYP27B1, HSF1, SP3, CCNF, PLCD3, SPINT1, EGLN1, CITED2 (10)
	GO: 0048701∼embryonic cranial skeleton morphogenesis	DLX2, TULP3, NDST1, TGFBR2, GAS1 (5)
	GO: 0060136∼embryonic process involved in female pregnancy	HSF1, SP3, CITED2 (3)