Potential Predictors of Poor Prognosis among Severe COVID-19 Patients: A Single-Center Study

Table 1

Patients’ demographics, clinical data, and laboratory data.

	Medians (interquartile ranges)	Frequencies		Cutoff
		N	%
Age (years)	M: 53 ± 15^†; F: 59 ± 20^†; All: 56 ± 17^†
20–59		106	66.3
≥60		54	33.8
Sex
Female		40	25
Male		120	75
Diabetes
Yes		52	32.5
No		108	67.5
Renal failure
Yes		5	3
No		155	97
Pulmonary disease
Yes		78	49
No		82	51
Heart disease
Yes		43	28
No		109	72
Ferritin	1229 (770–1853)			Male: 30–400 ug/L; Female: 15–150 ug/L
Normal		6	4
Increased		139	96
D-dimer	4 (2–12)			All: 0–0.55 mg/L
Normal		6	4
Increased		131	96
AST	58 (29–99)			All: 15–37 U/L
Normal		50	32
Increased		107	68
ALT	42 (27–92)			All: 14–36 U/L
Normal		103	66
Increased		52	34
ALP	24 (20–30)			All: 46–120 U/L
Decreased		146	100
Normal		0	0
Total protein	68 (63–71)			All: 64–82 g/L
Decreased		22	26
Normal		62	74
Bilirubin total	13 (8–22)			All: 0–18.7 umol/L
Normal		97	75
Increased		32	25
Bilirubin nonconjugated	6 (3–15)			3.4–12 umol/L
Normal		38	30
Increased		89	70
Creatinine	243 (114–508)			Male: 62–115 umol/L; Female: 44–90 umol/L
Normal		56	38
Increased		93	62
BUN	24 (9–39)			All: 2.6–6.4 mmol/L
Normal		47	32
Increased		102	68
CRP	8 (2–13)			All: 0–6 mg/L
Normal		53	42
Increased		74	58
RBCs	4 (3–5)			Male: 4.5–5.5 10^12/L; Female: 3.8–4.8 10^12/L
Decreased		90	57
Normal		67	43
Hb	97 (81–121)			Male: 130–170 g/L; Female: 120–150 g/L
Decreased		103	65
Normal		55	35
Neutrophils	89 (80–92)			2–7 10^9/L
Normal		41	29
Increased		102	71
Eosinophils	0 (0–2)			0.1–0.8 10^9/L
Decreased		89	62
Normal		54	38
Basophils	0 (0–0)			0.02–0.1 10^9/L
Decreased		105	73
Increased		38	27
Monocytes	4 (2–7)			0.2–1 10^9/L
Decreased		35	24
Normal		108	76
Lymphocytes	7 (4–13)			1–4 10^9/L
Decreased		119	83
Normal		24	17
Discharge status
Cured		67	42
Died		93	58
Overall		160	100

N: number of patients; M: male; F: female; all: both male and female; SD: standard deviation; BUN: blood urea nitrogen; CRP: C-reactive protein; Hb: hemoglobin; AST: aspartate aminotransferase; ALT: alanine aminotransferase; ALP: alkaline phosphatase. †Mean ± SD.Cutoff for laboratory tests.