A Cross-Sectional Comparative Study of the Performance of the Widal Test and the Typhidot Immunoassay for Typhoid Fever Diagnosis in the West Region of Cameroon

Table 4

Performance of the Widal test and Typhidot immunoassay against the reference standard for the diagnosis of typhoid fever.

Stool culture		value	Sen	Spec	PPV	NPV	LHR	Accu	Kappa (95% CI)	Agreement (%)
Pos	Neg
Widal
67	253	<0.0001	0.938 (0.87–0.98)	0.478 (0.44–0.53)	0.211 (0.17–0.26)	0.980 (0.96–0.99)	1.829	0.543	0.167 (0.12–0.21)	53.76
5	233
Typhidot-IgM
67	128	<0.0001	0.806 (0.70–0.88)	0.940 (0.92–0.96)	0.667 (0.56–0.76)	0.970 (0.95–0.98)	13.5	0.941	0.386	76.16
5	358								(0.31–0.46)

PPV: positive predictive value; NPV: negative predictive value; Pos: positive; Neg: negative; LHR: likelihood ratio; Accu: accuracy; Sen: sensitivity; Spec: specificity; IgM: immunoglobulin M.