Effect of Antifungal-Treated Host Macrophages on Candida glabrata

Figure 2

Effects of different antifungal drugs on the secretion of IL-6, IL-8, and TNF-α from macrophages infected by C. glabrata. The levels of secreted IL-6, IL-8, and TNF-α were determined by ELISA. IL-6 levels secreted by the four groups of macrophages were not statistically significant (^∗, ), and IL-6 levels secreted at different time points were significantly different (F = 6562.399, ^∗∗, ). At all-time points, IL-6 levels gradually increased over time (a). IL-8 levels secreted by the four groups of macrophages were not statistically significant (^∗, ), and IL-8 levels secreted at different time points were statistically significant (F = 828.076, ^∗∗, ). At all-time points, IL-8 levels fluctuated with time (b). TNF-α levels secreted at different time points were statistically significant (F = 2237.196, ^∗, ). At all-time points, TNF-α levels gradually increased over time (c).

(a)

(b)

(c)