Risk Factors and Outcome of Sepsis in Traumatic Patients and Pathogen Detection Using Metagenomic Next-Generation Sequencing

Table 1

Sequential organ failure assessment (SOFA).

Organ system	0	1	2	3	4
Respiratory: PaO2/FIO2 (mmHg)	> 400	≤400	≤300	≤200	≤100
Renal: Creatinine (mg/dl) or urine output	<1.2	1.2–1.9	2.0–3.4	3.5–4.9 or <500 ml/d	≥5.0 or <200 ml/d
Hepatic: Bilirubin (mg/dl)	<1.2	1.2–1.9	2.0–5.9	6.0–11.9	≥12.0
Cardiovascular: Hypotension	No hypotension	MAP<70 mmHg	Dopamine≤5 or dobutamine (any dose)^#	Dopamine>5 or epinephrine≤0.1 or norepinephrine≤0.1#	Dopamine>15 or epinephrine>0.1 or norepinephrine>0.1^#
Hematologic: Platelet count (×103/mm3)	> 150	≤150	≤100	≤50	≤20
Neurologic: Glasgow coma score	15	13–14	10–12	6–9	<6

With ventilatory support; ^#Adrenergic agents administered for at least 1 h (doses given are in µg/kg/min).