The Relation between Immunological Features and the Positive SARS-CoV-2 Nucleic Acid in Patients with Nonsevere COVID⁃19
Table 1
Patient demographics and baseline characteristics of nonsevere COVID-19.
All cases (n = 122), mean (CI 95%)
Mild cases (n = 38), mean (CI 95%)
Moderate cases (n = 84), mean (CI 95%)
value
Female, n (%)
40 (32.79%)
10 (26.32%)
30 (35.71%)
0.306
Age, median years (years)
37.21 (35.28–39.15)
32.16 (29.09–35.23)
39.50 (37.17–41.83)
<0.001
BMI value (kg/m2)
24.75 (24.05–25.45)
24.53 (23.02–26.04)
24.85 (24.07–25.62)
0.706
Smoker, n (%)
15 (12.30%)
7 (18.42%)
8 (9.52%)
0.232
Dyspepsia, n (%)
3 (2.46%)
1 (2.63%)
2 (2.38%)
1.000
Cough, n (%)
24 (19.67%)
9 (23.68%)
15 (17.86%)
0.453
Fever, n (%)
29 (23.77%)
12 (31.58%)
17 (20.24%)
0.173
Hyposmia, n (%)
10 (8.20%)
9 (23.68%)
1 (1.09%)
<0.001
Blood’s LYM, n ×n 109/L
1.94 (1.76–2.11)
2.42 (1.97–2.88)
1.72 (1.59–1.85)
0.004
ALT in serum (U/l)
36.38 (31.08–41.68)
35.17 (23.30–47.05)
36.92 (31.21–42.63)
0.764
AST in serum (U/l)
29.10 (26.39–31.80)
31.08 (24.00–38.16)
28.20 (25.80–30.61)
0.441
ALB in serum (g/l)
45.51 (39.27–51.75)
54.53 (34.37–74.69)
41.43 (40.12–42.74)
0.197
IgM of COVID-19
17.20 (9.46–24.94)
7.41 (1.76–13.07)
21.63 (10.72–32.54)
0.023
IgG of COVID-19
24.42 (17.10–31.75)
15.13 (5.79–24.47)
28.63 (18.88–38.38)
0.047
CD4+T cell count (×106/L)
814.69 (704.69–924.68)
943.23 (753.01–1133.45)
756.54 (621.23–891.85)
0.120
CD8+T cell count (×106/L)
483.89 (423.31–544.46)
606.30 (477.12–735.47)
428.51 (364.25–492.77)
0.007
NPD, days
20.49 (17.50–3.49)
24.53 (14.32–28.21)
24.8 5 (17.01–23.27)
0.733
BMI, body mass index; LYM, absolute value of lymphocyte count; ALT, alanine aminotransferase; AST, aspartate aminotransferase; ALB, albumin; n, number; IgM, specific immunoglobulin M (IgM); IgG, specific immunoglobulin G; NPD, nucleic acid positive duration.
