| Characteristics | Total (n = 204) | Monomicrobial AB-BSI (n = 165) | Polymicrobial AB-BSI (n = 39) | value |
| Age, median years (IQR) | 65.00 (49.25,76.75) | 68.00 (53,77.50) | 58 (40.00,76.00) | 0.069 |
| Male, n (%) | 138 (67.6%) | 111 (67.3%) | 27 (69.2%) | 0.814 |
| Comorbidities, n (%) | Diabetes mellitus | 38 (18.6%) | 33 (20.0%) | 5 (12.8%) | 0.300 | Chronic kidney disease | 22 (10.8%) | 18 (10.9%) | 4 (10.3%) | 0.906 | Chronic liver disease | 25 (12.3%) | 18 (10.9%) | 7 (17.9%) | 0.228 | COPD or severe asthma | 21 (10.3%) | 18 (10.9%) | 3 (7.7%) | 0.552 | Chronic cardiac insufficiency | 33 (16.2%) | 27 (16.4%) | 6 (15.4%) | 0.881 | Hypertension | 73 (35.8%) | 59 (35.8%) | 14 (35.9%) | 0.987 | Solid tumor | 24 (11.8%) | 21 (12.7%) | 3 (7.7%) | 0.380 |
| Trauma | 56 (27.5%) | 37 (22.4%) | 19 (48.7%) | | Gastrointestinal hemorrhage | 33 (16.2%) | 24 (14.5%) | 9 (23.1%) | 0.193 | Burn injury | 35 (17.2%) | 20 (12.1%) | 15 (38.5%) | | Long-term corticoid treatment | 43 (21.1%) | 34 (20.6%) | 9 (23.1%) | 0.734 | Cerebrovascular accident | 34 (16.7%) | 31 (18.8%) | 3 (7.7%) | 0.094 |
| CCI, median (IQR) | 3 (1.25,6) | 4 (2,6) | 2 (1,5) | 0.077 |
| APACHE II score, median (IQR) | 14 (10,19.75) | 14 (10,20) | 14 (10,17) | 0.482 |
| SOFA score, median (IQR) | 4 (2,7) | 4 (2,7) | 4 (2,7) | 0.768 |
| Pitt bacteremia score, median (IQR) | 3 (1,4) | 3 (1,4) | 3 (2,4) | 0.759 |
| Hospitalization ward, n (%) | ICU stay | 96 (47.1%) | 78 (47.3%) | 18 (46.2%) | 0.900 |
| Previous treatment, n (%) | Parenteral nutrition | 106 (52%) | 84 (50.9%) | 22 (56.4%) | 0.749 | Mechanical ventilation | 103 (50.5%) | 82 (49.7%) | 21 (53.8%) | 0.641 | Antibiotic exposure | 175 (86.2%) | 140 (85.4%) | 35 (89.7%) | 0.476 |
| Surgery | 73 (35.8%) | 54 (32.7%) | 19 (48.7%) | 0.061 | Renal replacement therapy | 18 (8.8%) | 15 (9.1%) | 3 (7.7%) | 0.396 | Blood transfusion | 91 (44.6%) | 68 (41.2%) | 23 (59%) | |
| Invasive devices, n (%) | | | | | Central line | 168 (82.4%) | 133 (80.6%) | 35 (89.7%) | 0.178 | Indwelling urinary catheter | 157 (77.0%) | 122 (73.9%) | 35 (89.7%) | | Intraperitoneal drainage | 28 (13.7%) | 20 (12.1%) | 8 (20.5%) | 0.171 |
| Prior hospital stays, median days (IQR) | 13 (7,26) | 12 (6,27) | 16 (7,25) | 0.327 |
| Nosocomial infection, n (%) | 124 (60.8%) | 95 (57.6%) | 29 (74.4%) | 0.054 |
| Delayed antibiotic therapy, n (%) | 19 (9.3%) | 16 (9.7%) | 3 (7.7%) | 0.698 |
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