Research Article

Polymorphism of E6 and E7 Genes in Human Papillomavirus Types 31 and 33 in Northeast China

Table 2

Nucleotide sequence mutations of HPV31E6.

CategoryNucleotide positionn (151)Lineage
112127698190141154178190202207213219297321331368375383391409413430439

Reference J04353.1AATCATTACAATAAGATACTAACCAA
HPV31E60116A
HPV31E602TTGAGT21C
HPV31E603TTAT2C
HPV31E604TTAGT29C
HPV31E605CGTGT6B
HPV31E606T49A
HPV31E607TTAGGT1C
HPV31E608CGTGT9B
HPV31E609TT1A
HPV31E610GTTAGTG1C
HPV31E611TTGAGTT1C
HPV31E612TTAGCT1C
HPV31E613GTTAGCT1C
HPV31E614CTTGAGT1C
HPV31E615A6A
HPV31E616TCTGAGT1C
HPV31E617TT1A
HPV31E618TTGAGCT1C
HPV31E619TCTGAGT2C
HPV31E620C1A
aa mutationAmino acid position
479232730475260646869717399107111123125128131137138144147
Reference J04353.1NEPYRCFIHTRFSVLQCKFIRIART
TLYARRTVVCA
Protein secondary structureCEEHCCECCCC

Dashes (−) represent that nucleotides are identical to the reference sequence. Nucleotide mutations are presented by the corresponding letters. aa, amino acid. “n” represents the number of each species among the samples examined. C, random coil; E, extended strand; H, alpha helix.