Similarities and Differences among Species Closely Related to Candida albicans: C. tropicalis, C. dubliniensis, and C. auris

Figure 3

Selected factors of C. tropicalis (Ct), C. dubliniensis (Cd), and C. auris (Cau) related to their interaction with the environment and the host. The development of a fungal infection can enhance (green arrow) or inhibit (red arrow) some processes related to the host’s immune response, and it differs depending on the species causing the candidiasis. In addition, the adaptation of the pathogen to the new environment influences the increase (green arrow) or decrease in the expression of genes (red arrow) involved in its metabolism. In turn, the variable repertoire of secreted quorum sensing molecules favors or inhibits fungal filamentation and biofilm formation (green and red arrows, respectively). The use of external farnesol for testing.