Research Article

Molecular Modeling Guided Drug Designing for the Therapeutic Treatment of Rheumatoid Arthritis

Table 3

Characteristics of properties of IL-6 predicted by ProtParam.

Sr. no.PropertyValue

1Residues185
2Total atoms2956
3Theoretical pI6.22
4Molecular weight20980.97
5Aliphatic index84.43
6Extinction coefficient10220 at Abs 0.1% 0.487, assuming all pairs of Cys residues form cystines
7ChargeNegative
8Instability index59.45
9Grand average of hydropathicity (GRAVY)-0.498
10Chemical formulaC917H1487N255O288S9