Research Article
Molecular Modeling Guided Drug Designing for the Therapeutic Treatment of Rheumatoid Arthritis
Table 6
Physicochemical properties and drug toxicity liability profiling of identified hits.
HIA: human intestinal absorption; HOB: human oral bioavailability; ERB: estrogen receptor binding; ARB: androgen receptor binding; TRB: thyroid receptor binding; hERG CI: human ether-a-go-go-related gene channel inhibition; green color: potentially liable with transporter/channel; light green color: liable with transporter/channel; red color: does not show liability with transporters; light red color: slightly shows transporter liability. |