Research Article

Mycobacterium avium Infection of Multinucleated Giant Cells Reveals Association of Bacterial Survival to Autophagy and Cholesterol Utilization

Figure 6

Gene expression of autophagic markers is elevated in MGCs. Either MGCs or THP-1 cells were infected with WT M. avium A5 for 4 h. (a) Beclin-1 transcripts were measured by RT-qPCR at indicated times. mRNA levels are presented as relative expression to actin. (b) LC3 transcripts were measured at indicated time points. mRNA levels are represented relative to actin expression. Data are representative of two independent experiments. Statistical comparisons: ; ; .
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