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Contrast Media & Molecular Imaging
Volume 2017, Article ID 1686525, 11 pages
Research Article

MicroPET/CT Imaging of AXL Downregulation by HSP90 Inhibition in Triple-Negative Breast Cancer

1Department of Cancer Systems Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
2Department of Radiology, The 1st Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China
3Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA

Correspondence should be addressed to Yongqiang Yu; moc.361.piv@gnaiqgnoyuy.rjc, Shiaw-Yih Lin; gro.nosrednadm@nilys, and Chun Li; gro.nosrednadm@ilc

Received 7 February 2017; Accepted 2 April 2017; Published 14 May 2017

Academic Editor: Kai Yang

Copyright © 2017 Wanqin Wang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Supplementary Materials include regents and antibodies used, pharmacokinetics, and figures of radiochemistry reaction scheme, radiolabeling efficiency, radiotracer stability, blood activity-time curve, and schematic illustration of the mechanism of 17-AAG induced AXL degradation.

  1. Supplementary Material