Clinical Study

Head-to-Head Comparison of 68Ga-Citrate and 18F-FDG PET/CT for Detection of Infectious Foci in Patients with Staphylococcus aureus Bacteraemia

Figure 1

Patient #1 was a 66-year-old woman (weight: 65 kg) who presented at the hospital because of back pain and general symptoms. Both 68Ga-citrate (a) and 18F-FDG PET/CT (b) showed vertebral osteomyelitis (spondylodiscitis; red arrowheads) and abscesses in the iliopsoas and paravertebral area (red arrows). These were confirmed by MRI (c). 18F-FDG PET/CT also showed other multiple soft tissue infectious foci ((b), blue arrows), some of which were not detectable on 68Ga-citrate PET/CT ((a), blue arrow). The injected radioactivity dose of 18F-FDG was 227 MBq and the PET acquisition started 54 min after injection. The injected radioactivity dose of 68Ga-citrate was 245 MBq and the PET acquisition started 88 min after injection. MRI sequences were as follows: T2-weighted short inversion time inversion recovery (STIR) on the coronal view image (left) and T2-weighted on the sagittal view image (right).