Head-to-Head Comparison of ⁶⁸Ga-Citrate and ¹⁸F-FDG PET/CT for Detection of Infectious Foci in Patients with Staphylococcus aureus Bacteraemia

Figure 2

Patient #2 was a 70-year-old woman (weight: 69 kg), with multiple background diseases, who was admitted to hospital because of back pain and high fever. Both ⁶⁸Ga-citrate (a, c, e) and ¹⁸F-FDG PET/CT (b, d, f) showed vertebral osteomyelitis (spondylodiscitis) in Th12 (red arrows) and pneumonia in both lungs. MRI showed oedema in Th12 (g, h). ⁶⁸Ga-citrate PET/CT also revealed uptake in the left parotid gland (unspecific; (a), blue arrow), neck lymph nodes (reactive), and inferior vena cava (thrombosis; (e), blue arrow). There was no ¹⁸F-FDG uptake in these areas. The injected radioactivity dose of ¹⁸F-FDG was 279 MBq and the PET acquisition started 50 min after injection. The injected radioactivity dose of ⁶⁸Ga-citrate was 199 MBq and the PET acquisition started 100 min after injection. MRI sequences were as follows: T2-weighted short inversion time inversion recovery (STIR) on the coronal view image (left) and T2-weighted on the sagittal view image (right).