Preliminary ¹⁹F-MRS Study of Tumor Cell Proliferation with 3′-deoxy-3′-fluorothymidine and Its Metabolite (FLT-MP)

Figure 2

Typical coil-localized ¹⁹F spectra of (a) FLT and (b) FLT-MP containing TFA as a reference. (c) ¹⁹F MR images of phantoms containing 25, 50, 100, and 200 mM FLT. (d) Signal intensity in ¹⁹F MR images of FLT phantoms, as a function of FLT concentration (). (e) Typical coil-localized ¹⁹F spectrum of a phantom containing a mixture of FLT (100 mM) and FLT-MP (60 mM). (f) ¹⁹F MRS spectrum of a phantom containing a mixture of FLT (100 mM) and FLT-MP (60 mM). The area ratio of FLT (100 mM) to FLT-MP (60 mM) is approximately 100 to 60.

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