A First Report on [¹⁸F]FPRGD₂ PET/CT Imaging in Multiple Myeloma

Figure 4

FPRG PET/CT images of all patients. A diffuse bone marrow involvement was described based on CT images in patients #1 (a) and #2 (b); the FPRG PET images also showed diffuse and heterogeneous bone marrow FPRG uptake in patients #1 (a) and a mild diffuse bone marrow uptake in patient #2 (b). In contrast, no diffuse bone marrow FPRG uptake was seen in patients #3 ((c) the green arrows point at a lytic FL with FPRG uptake) and #4 ((d) no lesion shown). Note that, in patient #1 (a) with newly diagnosed MM, a large osteolytic FL in CT images did not show FPRG uptake above the bone marrow background ((a) red arrows).

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