In Vivo PET Imaging of Adenosine 2A Receptors in Neuroinflammatory and Neurodegenerative Disease

Figure 1

MRI and [¹¹C]TMSX PET images of a healthy subject. Axial T1 gadolinium-enhanced weighted MR image (a) and corresponding parametric [¹¹C]TMSX PET image (b). [¹¹C]TMSX uptake is visualized as voxelwise distribution volume (V_T) denoted by the color scale on the right. Strong binding to receptors is seen in the striatum, where receptors are expressed on striatopallidal medium spiny neurons.

(a)

(b)