Clinical Applications of Contrast-Enhanced Perfusion MRI Techniques in Gliomas: Recent Advances and Current Challenges

<div>An illustration of parameters derived from DCE-MRI and DSC-MRI. (a) Semiquantitative parameters from signal intensity curve in DCE-MRI. (b) Schematic diagram of ETK model from DCE-MRI. (c) Calculation of PSR and PH from DSC-MRI. (d) Contrast concentration-time course curve of DSC-MRI. CBV is proportional to determined area under contrast concentration-time course curve (blue shaded area), and CBF is easily calculated given the relationship of MTT and CBV.</div>

Contrast Media & Molecular Imaging

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Figure 2: Clinical Applications of Contrast-Enhanced Perfusion MRI Techniques in Gliomas: Recent Advances and Current Challenges 