Labelling of <svg xmlns:xlink="http://www.w3.org/1999/xlink" xmlns="http://www.w3.org/2000/svg" style="vertical-align:-0.06579971pt" id="M1" height="15.3182pt" version="1.1" viewBox="-0.0657574 -15.2524 13.0148 15.3182" width="13.0148pt"><g transform="matrix(.012,0,0,-0.012,0,-7.578)"><path id="g22-55" d="M257 635C101 635 25 509 25 419C25 312 99 229 220 229C237 229 254 234 278 246L328 272C302 155 197 53 48 27L55 -15C99 -14 188 2 228 18C369 73 478 199 478 382C478 518 403 635 257 635ZM236 589C313 589 339 482 339 386C339 366 338 342 334 315C320 309 304 303 279 303C206 303 159 375 159 459C159 522 183 589 236 589Z"/></g><g transform="matrix(.012,0,0,-0.012,6.09,-7.578)"><path id="g22-46" d="M255 635C86 635 29 459 29 311C29 167 83 -12 254 -12S478 166 478 312C478 457 425 635 255 635ZM252 588C317 588 338 455 338 314C338 176 322 35 256 35C191 35 169 183 169 315C169 448 185 588 252 588Z"/></g></svg>Y- and <svg xmlns:xlink="http://www.w3.org/1999/xlink" xmlns="http://www.w3.org/2000/svg" style="vertical-align:-0.06579971pt" id="M2" height="15.3182pt" version="1.1" viewBox="-0.0657574 -15.2524 19.1277 15.3182" width="19.1277pt"><g transform="matrix(.012,0,0,-0.012,0,-7.578)"><path id="g22-47" d="M415 0V41C335 46 327 62 327 127V635C236 611 161 593 93 583V547L150 544C187 541 192 535 192 483V127C192 59 182 46 102 41V0H415Z"/></g><g transform="matrix(.012,0,0,-0.012,6.09,-7.578)"><path id="g22-53" d="M482 623L67 622C60 580 54 527 40 445H81C108 505 116 513 184 513H391C306 352 206 176 87 2L95 -12L203 0C294 205 397 410 492 611L482 623Z"/></g><g transform="matrix(.012,0,0,-0.012,12.18,-7.578)"><use xlink:href="#g22-53"/></g></svg>Lu-DOTA-Bioconjugates for Targeted Radionuclide Therapy: A Comparison among Manual, Semiautomated, and Fully Automated Synthesis

<div>Comparison between the fingertips exposure of the operators during preparation of yttrium-90 (<svg height="8.32035pt" id="M56" style="vertical-align:-0.2063999pt" version="1.1" viewbox="-0.0498162 -8.11395 34.1002 8.32035" width="34.1002pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M495 86L479 114C446 82 419 66 409 66C401 66 401 72 406 97C420 166 436 231 453 297C489 435 454 448 428 448C406 448 384 439 354 422C305 394 222 327 161 247H159L183 345C200 415 194 448 173 448C143 448 82 410 23 351L38 325C64 349 95 371 105 371C111 371 116 365 109 336L25 -4L31 -12C50 -4 77 3 107 9C119 69 132 122 145 168C197 254 321 381 370 381C387 381 393 374 378 305L329 95C309 17 320 -12 345 -12C372 -12 430 19 495 86Z" id="g113-111"></path><glyph.data ascent="3473" descent="-2876" horiz-adv-x="502" vert-adv-y="502"></glyph.data></g><g transform="matrix(.013,0,0,-0.013,10.158,0)"><path d="M535 323V373H52V323H535ZM535 138V188H52V138H535Z" id="g117-34"></path><glyph.data ascent="3473" descent="-2876" horiz-adv-x="587" vert-adv-y="587"></glyph.data></g><g transform="matrix(.013,0,0,-0.013,21.421,0)"><path d="M447 623H65C61 580 56 530 47 475H76C100 541 106 550 172 550H388C308 376 196 170 91 -1L98 -12L172 -2C268 204 360 408 455 611L447 623Z" id="g113-56"></path><glyph.data ascent="3473" descent="-2876" horiz-adv-x="480" vert-adv-y="480"></glyph.data></g><g transform="matrix(.013,0,0,-0.013,27.663,0)"><path d="M447 623H65C61 580 56 530 47 475H76C100 541 106 550 172 550H388C308 376 196 170 91 -1L98 -12L172 -2C268 204 360 408 455 611L447 623Z" id="g113-56"></path><glyph.data ascent="3473" descent="-2876" horiz-adv-x="480" vert-adv-y="480"></glyph.data></g></svg>, 63, and 24 for manual, semiautomated and automated approach, resp.) and lutetium-177 (<svg height="8.55521pt" id="M57" style="vertical-align:-0.2063904pt" version="1.1" viewbox="-0.0498162 -8.34882 34.1002 8.55521" width="34.1002pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M495 86L479 114C446 82 419 66 409 66C401 66 401 72 406 97C420 166 436 231 453 297C489 435 454 448 428 448C406 448 384 439 354 422C305 394 222 327 161 247H159L183 345C200 415 194 448 173 448C143 448 82 410 23 351L38 325C64 349 95 371 105 371C111 371 116 365 109 336L25 -4L31 -12C50 -4 77 3 107 9C119 69 132 122 145 168C197 254 321 381 370 381C387 381 393 374 378 305L329 95C309 17 320 -12 345 -12C372 -12 430 19 495 86Z" id="g113-111"></path><glyph.data ascent="3473" descent="-2876" horiz-adv-x="502" vert-adv-y="502"></glyph.data></g><g transform="matrix(.013,0,0,-0.013,10.158,0)"><path d="M535 323V373H52V323H535ZM535 138V188H52V138H535Z" id="g117-34"></path><glyph.data ascent="3473" descent="-2876" horiz-adv-x="587" vert-adv-y="587"></glyph.data></g><g transform="matrix(.013,0,0,-0.013,21.421,0)"><path d="M456 178V225H360V632H320C217 496 115 347 20 206V178H280V106C280 40 276 34 189 27V0H445V27C364 34 360 39 360 106V178H456ZM280 225H82C149 335 214 431 278 520H280V225Z" id="g113-53"></path><glyph.data ascent="3473" descent="-2876" horiz-adv-x="480" vert-adv-y="480"></glyph.data></g><g transform="matrix(.013,0,0,-0.013,27.661,0)"><path d="M285 378C315 398 338 416 353 432C373 451 384 474 384 503C384 579 325 635 236 635H235C182 635 136 610 108 579L65 516L85 496C110 533 150 575 205 575C258 575 300 543 300 481C300 407 232 369 141 339L147 310C163 315 188 321 211 321C268 321 338 284 338 192C338 94 288 40 217 40C160 40 119 68 93 91C85 98 77 97 69 91C60 84 47 71 46 58C44 46 48 35 62 22C75 10 116 -12 162 -12C234 -12 424 62 424 224C424 297 373 359 285 376V378Z" id="g113-52"></path><glyph.data ascent="3473" descent="-2876" horiz-adv-x="480" vert-adv-y="480"></glyph.data></g></svg>, 88, and 26 for manual, semiautomated and automated approach, resp.) labelled radiopharmaceuticals using three approach. Data are reported as means; SDs are omitted for clarity.</div>

Contrast Media & Molecular Imaging

fig8

Figure 8

Figure 8: Labelling of <svg xmlns:xlink="http://www.w3.org/1999/xlink" xmlns="http://www.w3.org/2000/svg" style="vertical-align:-0.06579971pt" id="M1" height="15.3182pt" version="1.1" viewBox="-0.0657574 -15.2524 13.0148 15.3182" width="13.0148pt"><g transform="matrix(.012,0,0,-0.012,0,-7.578)"><path id="g22-55" d="M257 635C101 635 25 509 25 419C25 312 99 229 220 229C237 229 254 234 278 246L328 272C302 155 197 53 48 27L55 -15C99 -14 188 2 228 18C369 73 478 199 478 382C478 518 403 635 257 635ZM236 589C313 589 339 482 339 386C339 366 338 342 334 315C320 309 304 303 279 303C206 303 159 375 159 459C159 522 183 589 236 589Z"/></g><g transform="matrix(.012,0,0,-0.012,6.09,-7.578)"><path id="g22-46" d="M255 635C86 635 29 459 29 311C29 167 83 -12 254 -12S478 166 478 312C478 457 425 635 255 635ZM252 588C317 588 338 455 338 314C338 176 322 35 256 35C191 35 169 183 169 315C169 448 185 588 252 588Z"/></g></svg>Y- and <svg xmlns:xlink="http://www.w3.org/1999/xlink" xmlns="http://www.w3.org/2000/svg" style="vertical-align:-0.06579971pt" id="M2" height="15.3182pt" version="1.1" viewBox="-0.0657574 -15.2524 19.1277 15.3182" width="19.1277pt"><g transform="matrix(.012,0,0,-0.012,0,-7.578)"><path id="g22-47" d="M415 0V41C335 46 327 62 327 127V635C236 611 161 593 93 583V547L150 544C187 541 192 535 192 483V127C192 59 182 46 102 41V0H415Z"/></g><g transform="matrix(.012,0,0,-0.012,6.09,-7.578)"><path id="g22-53" d="M482 623L67 622C60 580 54 527 40 445H81C108 505 116 513 184 513H391C306 352 206 176 87 2L95 -12L203 0C294 205 397 410 492 611L482 623Z"/></g><g transform="matrix(.012,0,0,-0.012,12.18,-7.578)"><use xlink:href="#g22-53"/></g></svg>Lu-DOTA-Bioconjugates for Targeted Radionuclide Therapy: A Comparison among Manual, Semiautomated, and Fully Automated Synthesis 

Figure 8 | Labelling of Y- and Lu-DOTA-Bioconjugates for Targeted Radionuclide Therapy: A Comparison among Manual, Semiautomated, and Fully Automated Synthesis 