Research Article
F-18 FP-CIT PET in Multiple System Atrophy of the Cerebellar Type: Additional Role in Treatment
Table 1
Difference in characteristics of the patients between normal and abnormal scan groups.
| | Characteristics | Normal scan
() | Abnormal scan
() | |
| | Age (years) | 61.7 ± 6.6 | 61.5 ± 6.5 | 0.9272 | | Sex (male : female) | 18 : 7 | 12 : 12 | 0.0939 | | Disease duration (years) | 3.1 ± 1.5 | 3.0 ± 1.6 | 0.8441 | | Parkinsonism | 8 (32.0%) | 16 (66.7%) | 0.0163 | | Bradykinesia | 14 (56.0%) | 22 (91.7%) | 0.0082 | | Bradykinesia (score) | 1.0 ± 0.9 | 1.6 ± 0.8 | 0.0142 | | Rigidity | 8 (32.0%) | 20 (83.3%) | 0.0004 | | Rigidity (score) | 0.3 ± 0.5 | 0.9 ± 0.5 | 0.0003 | | Postural instability | 17 (68.0%) | 24 (100.0%) | 0.0040 | | Resting tremor | 4 (16.0%) | 7 (29.2%) | 0.3209 | | Cerebellar symptom | | | | | Gait ataxia | 25 (100.0%) | 24 (100.0%) | 1.0000 | | Limb ataxia | 22 (88.0%) | 22 (91.7%) | 1.0000 | | Cerebellar dysarthria | 22 (88.0%) | 23 (95.8%) | 1.0000 | | Oculomotor dysfunction | 18 (72.0%) | 22 (91.7%) | 0.1383 | | Autonomic symptom | | | | | Orthostatic hypotension | 12 (48.0%) | 9 (36.0%) | 0.4624 | | Urinary incontinence | 10 (40.0%) | 13 (54.2%) | 0.3255 | | Erectile dysfunction | 10/18 (55.6%) | 9/12 (75.0%) | 0.4425 | | PET parameter | | | | | Striatal asymmetry | 0.97 ± 0.03 | 0.88 ± 0.10 | 0.0006 | | Striatal SUR | 3.98 ± 0.58 | 2.59 ± 0.89 | <0.0001 |
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value in bold, italic type indicates statistical significance. SUR: specific uptake ratio.
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