Correlation of Somatostatin Receptor-2 Expression with Gallium-68-DOTA-TATE Uptake in Neuroblastoma Xenograft Models

Figure 2

Representative micro-PET/CT images at 1 hour after injection of 10 MBq of  ⁶⁸Ga-DOTA-TATE in the CHLA-15 (a) and SK-N-BE(2) (b) tumor-bearing NOD/SCID mice. Images were presented in the axial (left) and coronal (right) orientations. The white arrows denote localized tumor on the shoulder. (c) Standardized Uptake Values (SUV) in CHLA-15 and SK-N-BE(2) xenografts were calculated using the formula: . The difference was significant between CHLA-5 and SK-N-BE(2) tumors (). Two-tailed unpaired -tests were performed to compare the values obtained.

(a)

(b)

(c)