Research Article
Influence of Molecular Mobility on Contrast Efficiency of Branched Polyethylene Glycol Contrast Agent
Table 1
Summary of the synthesized PEG-Gd with different structures.
| | Product | MW (data sheet) | Gd introduction ratio (Gd/PEG (mol/mol)) (ICP-MS) | Zeta potential (mV) | Hydrodynamic radius (nm) | Yield (%) |
| | 8-arm (4.1) | 15000 | 4.07 | −0.22 | 2.90 | 90.7 | | 8-arm (3.7) | 15000 | 3.70 | −0.02 | 3.05 | 74.9 | | 8-arm (2.6) | 15000 | 2.64 | −0.02 | 2.24 | 94.8 | | 8-arm (1.8) | 15000 | 1.79 | 0.08 | 2.70 | 97.2 | | 4-arm (2.0) | 15000 | 1.97 | 0.04 | 4.04 | 42.6 | | Dendron (0.7) | 40000 | 0.69 | −0.08 | 11.72 | 99.2 | | Linear (0.7) | 10000 | 0.70 | −1.73 | 4.00 | 54.2 | | Magnescope | 559 | — | −0.11 | 0.99 | — | | ProHance | 559 | — | 0.18 | 1.07 | — |
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