Measuring Tumor Metabolism in Pediatric Diffuse Intrinsic Pontine Glioma Using Hyperpolarized Carbon-13 MR Metabolic Imaging

Figure 1

Representative anatomical images from a rat ( total) bearing orthotopic DIPG. T₂-weighted images in sagittal (a) and axial (b) planes demonstrated a T₂-hyperintense lesion through the brainstem. The corresponding axial post-Gd T₁-weighted image (c) exhibited no contrast enhancement. Horizontal dashed lines in (a) delimit the 5.4 mm axial slice of ¹³C MRSI data, presented in Figure 2. The yellow boundary in (a) and (b) indicates the location of pons.

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