Sensitivity of Multiphase Pseudocontinuous Arterial Spin Labelling (MP pCASL) Magnetic Resonance Imaging for Measuring Brain and Tumour Blood Flow in Mice

Figure 4

Cerebral blood flow maps and regional values. (a) Representative CBF maps produced using gold-standard autoradiography (top row), and the optimised MP pCASL sequence (bottom row). (b) Regional CBF values as measured by MP pCASL and autoradiography (AR). Average CBF values were 96 ± 18 mL/100 g/min across the whole brain using MP pCASL, and 101 ± 32 mL/100 g/min using autoradiography. No significant differences were found between MP pCASL and autoradiography CBF measurements either for whole brain, or by region. CC–corpus callosum.

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