Cervical Cancer: Associations between Metabolic Parameters and Whole Lesion Histogram Analysis Derived from Simultaneous ¹⁸F-FDG-PET/MRI

Figure 1

Imaging and histopathological findings in a case of cervical cancer. (a) ¹⁸F-FDG-PET of a 57-year-old woman with locally advanced cervical cancer (arrow). (b) Fused ¹⁸F-FDG-PET/MRI image demonstration of the metabolic active uterine cervical cancer (arrow). Calculated ¹⁸F-FDG-PET parameters are as follows: SUV_max = 8.77, SUV_mean = 4.66, SUV median = 4.32, TLG = 92.91, and MTV = 19.96. (c) ADC map of the tumor with a ROI. (e) ADC histogram. The histogram analysis parameters (×10⁻³ mm²·s⁻¹) are as follows: ADC_min = 0.36, ADC_mean = 0.87, ADC_max = 1.36, p10 = 0.7, p25 = 0.78, p75 = 0.96, p90 = 1.03, median = 0.88, and mode = 0.93. Histogram-based characteristics are as follows: kurtosis = 2.96, skewness = −028, and entropy = 4.72. (d) Histopathological examination (hematoxylin and eosin-stained specimen) after tumor biopsy reveals a G2 cervical cancer.