Preclinical Evaluation of Radioiodinated Hoechst 33258 for Early Prediction of Tumor Response to Treatment of Vascular-Disrupting Agents

<div>Representative coronal SPECT/CT images of W256 tumor-bearing rats 3 h following injection of <sup>131</sup>I-H33258. Tumors were treated with vehicle or CA4P 24 h prior to injection of <sup>131</sup>I-H33258 and obvious tracer uptake was observed in CA4P treated tumor on right hind flank. Tumors are denoted by red arrows.</div>

Contrast Media & Molecular Imaging

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Figure 4

Figure 4: Preclinical Evaluation of Radioiodinated Hoechst 33258 for Early Prediction of Tumor Response to Treatment of Vascular-Disrupting Agents 