Research Article

177Lu-DOTA-HYNIC-Lys(Nal)-Urea-Glu: Biokinetics, Dosimetry, and Evaluation in Patients with Advanced Prostate Cancer

Table 2

Description of the reported disease of patients and the radiotracer used in each case for evaluation of the response to 177Lu-iPSMA therapy.

Patient no.AgeReported diseaseRadiotracer

186Prostate cancer, resistant to castration, with retroperitoneal, external, and common iliac bilateral chains lymph node metastases68Ga-iPSMA
272Prostate cancer, resistant to castration, with bone, lungs, liver, and lymph node metastases; right nephrectomy and adrenalectomy with resection of the diaphragm by tumor infiltration[99mTc]Tc-iPSMA
371Prostate cancer, resistant to castration, with bone and lymph node metastases[99mTc]Tc-iPSMA
461Prostate cancer with lymph node metastasis[99mTc]Tc-iPSMA
560Prostate cancer, resistant to castration, diabetes mellitus type 2, chronic kidney disease, kidney transplant, with liver, retroperitoneal, and left iliac chain lymph nodes and vertebral T6 metastases[99mTc]Tc-iPSMA
672Prostate cancer, resistant to castration, with inguinal lymph nodes and bone metastases; kidney cancer with left nephrectomy; gastric cancer68Ga-PSMA-11
758Prostate cancer, resistant to castration, with right sacrum bone metastasis; retroperitoneal, iliac bilateral chains, inguinal, and gluteus lymph node metastases, bladder and liver metastases (Ra-223 treatment)68Ga-PSMA-11
865Prostate cancer with liver and lymph node metastases68Ga-PSMA-11
966Prostate cancer, resistant to castration, with multiple bone metastases (radiotherapy treatment)68Ga-PSMA-11
1074Prostate cancer, resistant to castration, with multiple lymph node metastases (brachytherapy treatment)68Ga-iPSMA