Research Article

177Lu-DOTA-HYNIC-Lys(Nal)-Urea-Glu: Biokinetics, Dosimetry, and Evaluation in Patients with Advanced Prostate Cancer

Table 4

PSA levels in patients before and after treatment.

Patient no. (no. of cycles, total activity administered (GBq))PSA levels (ng/mL) (SUVmax in soft tissue tumor lesions)
Before treatmentAfter treatment

1 (4, 18.5)58 (73)4 (1)
2 (2, 7.4)53 (32)55 (14)
3 (2, 7.4)20 (33)30 (17)
4 (1, 5.5)31 (46)18 (4)
5 (1, 7.4)101 (38)45 (16)
6 (2, 7.4)46 (33)25 (19)
7 (2, 7.4)217 (56)322 (21)
8 (2, 7.4)34 (47)11 (26)
9 (1, 7.4)37 (101)40 (33)
10 (1, 3.7)182 (79)76 (28)

Progressive disease: bone metastases.