Review Article

Molecular Imaging of Aminopeptidase N in Cancer and Angiogenesis

Figure 4

Bioluminescence imaging of APN enzyme activity in an ovarian cancer tumor mouse model. (a) Imaging with the L-leucine-aminoluciferin probe. (b) Blocked imaging of the L-leucine-aminoluciferin probe with an APN inhibitor. Reprinted (adapted) with permission from Li et al. [41], copyright (2014) from American Chemical Society.