Assessment of Liver Function Using Pharmacokinetic Parameters of Gd-EOB-DTPA: Experimental Study in Rat Hepatectomy Model

Table 3

The effects of hepatic resection on pharmacokinetic parameters of Gd-EOB-DTPA.

	Overall	Pairwise group
		Control; versus 70% H	70% H; versus 90% H	Control; versus 90% H
(μmol⋅min/L)	<.001	.394	<.001	<.001
(μmol⋅min/L)	.019	1.000	.001	<.001
(%)	<.001	1.000	<.001	<.001
/Dose (μmol⋅min/L/μmol)	<.001	1.000	<.001	<.001
(μmol/L)	<.001	.785	.007	<.001
/Dose (μmol/L/μmol)	<.001	.172	.007	<.001
CL (ml/min)	<.001	<.001	<.001	<.001
(mL)	<.001	<.001	.031	<.001
(mL)	<.001	<.001	.030	<.001
(min)	<.001	1.000	.002	.001
(min)	<.001	1.000	<.001	<.001

-way analysis of variance; hoc pairwise group comparisons by using Student’s test with Bonferroni correction; H: hepatectomy.