Functionalization of Gadolinium Chelates Silica Nanoparticle through Silane Chemistry for Simultaneous MRI/⁶⁴Cu PET Imaging

Figure 4

Simultaneous MRI/PET coronal images of mice bearing TS/A tumors (white arrows) after being injected with SiGdNP @ N-1(⁶⁴Cu) nanoparticle. (a) Control T₁-weighted MRI image of a healthy mouse; (b) T₁-MRI; (c) PET, and (d) merged images of tumor bearing mouse 1 h after injection; (e) T₁-MRI; (f) PET and (g) merged images of TS/A of tumor bearing mouse at 24 hours after injection.

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