Preparation of ⁶⁸Ga-PSMA-11 with a Synthesis Module for Micro PET-CT Imaging of PSMA Expression during Prostate Cancer Progression

Figure 3

The 3D views of representative micro PET-CT images of nude mice bearing PC-3, CWR22Rv1, LNCaP, and LNCaP xenografts with low dose (2.5 μg) or high dose (250 μg) preinjection of 2-PMPA (from left to right). PET-CT scan was performed 1 h after intravenous injection of  ⁶⁸Ga-PSMA-11 with preinjection of overdose 2-PMPA to verify its specific binding to PSMA.