Contrast Media & Molecular Imaging

Clinical Study

Iso-Osmolar Iodixanol Induces Less Increase in Circulating Endothelial Microparticles In Vivo and Less Endothelial Apoptosis In Vitro Compared with Low-Osmolar Iohexol

Table 1

Patients’ baseline characteristics.


Variates	Group I	Group II	Group III

	50	50	49	/
Male, (%)	28 (56.0)	31 (62.0)	37 (75.5)	0.116
Age, years	68.6 ± 8.8	68.6 ± 9.4	68.5 ± 9.5	0.998
BMI, kg/m²	25.1 ± 3.0	24.6 ± 2.6	24.9 ± 3.1	0.767
HBP, (%)	41 (82.0)	43 (86.0)	35 (71.4)	0.175
Smoking history, (%)	18 (36.0)	17 (34.0)	24 (49.0)	0.256
Family history, (%)	33 (66.0)	33 (66.0)	25 (51.0)	0.212
Total cholesterol, mmol/L	4.1 ± 1.2	3.9 ± 0.9	3.9 ± 0.9	0.571
Total triglyceride, mmol/L	1.3 ± 1.7	1.3 ± 1.7	1.3 ± 1.7	0.999
HDL-C, mmol/L	1.2 ± 1.3	1.2 ± 1.2	1.2 ± 1.2	0.695
LDL-C, mmol/L	2.3 ± 1.6	2.1 ± 1.3	2.0 ± 1.4	0.216
hsCRP, mg/L	1.3 ± 4.3	1.8 ± 5.4	1.3 ± 4.0	0.495
Fasting blood glucose, mmol/L	7.1 ± 1.4	7.2 ± 1.3	5.3 ± 1.2	<0.001
Blood urea nitrogen, mmol/L	5.3 (4.6, 6.5)	6.0 (5.0, 7.6)	5.1 (3.8, 6.1)	0.003
Creatinine, µmol/L	66.5 (59.8, 76.3)	72.9 (62.5, 89.4)	73.0 (62.0, 85.0)	0.046
ALT, U/L	18.5 (13.0, 25.8)	17.5 (13.0, 25.0)	18.0 (14.0, 23.5)	0.694
AST, U/L	19.5 (17.0, 23.3)	19.0 (15.8, 23.3)	20.0 (17.5, 23.5)	0.209
CK-MB, ng/mL	1.9 (1.1, 3.2)	2.0 (1.3, 3.6)	1.8 (1.2, 3.8)	0.846
Troponin-T, ng/mL	0.01 (0.01, 0.05)	0.01 (0.00, 0.03)	0.01 (0.00, 0.04)	0.223
Lesion arteries,	2.0 (2.0, 3.0)	3.0 (2.0, 4.0)	2.0 (1.0, 3.0)	0.151
Implanted stents,	1.0 (1.0, 1.0)	1.0 (1.0, 2.0)	1.0 (1.0, 2.0)	0.388
Gensini Score	27.7 ± 2.0	28.1 ± 2.4	28.7 ± 1.9	0.970
Volume of contrast media, mL	150.0 (150.0, 150.0)	150.0 (150.0, 150.0)	150.0 (150.0,150.0)	0.570

Normal data are represented by mean ± SD, nonnormal variates are repressed as median (interquartile range), and categorical variables are expressed as percentage. BMI: body mass index; HBP: high blood pressure; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; hsCRP: high sensitivity C-reactive protein; ALT: alanine aminotransferase; AST: aspartate aminotransferase; CK-MB: creatine kinase isoenzyme MB.