InVivo Molecular Ultrasound Assessment of Glioblastoma Neovasculature with Endoglin-Targeted Microbubbles

<div>Principal of the quantitative assessment of molecular US signals. (a) Burst-and-replenishment technique for the quantitative assessment of the attached MBs; (b) the differential targeted enhancement (dTE) would be used to indicate the molecular US signal which is contributed by attached MBs only. The nontargeted MBs were used as a reference for the CD105-targeted MBs.</div>

Contrast Media & Molecular Imaging

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Figure 5

Figure 5: InVivo Molecular Ultrasound Assessment of Glioblastoma Neovasculature with Endoglin-Targeted Microbubbles