Metabolic Volumetric Parameters in ¹¹C-Choline PET/MR Are Superior PET Imaging Biomarkers for Primary High-Risk Prostate Cancer

Figure 2

Simultaneous ¹¹C-choline PET/MRI images of the prostate region of a 74-year-old man with prostate cancer. (a) PET, (b) T2WI, (c) DWI, b=1000, (d) ADC, (e) DCE, (f) Ktrans, (g) Kep, and (h) iAUC maps derived from DCE showing tumor invasion of the left levator ani muscle (small arrows) and left gross extracapsular extension (arrowheads) by the primary tumor and bone metastasis at the sacrum (large arrows). Liver metastasis is also depicted on PET/MRI (not shown), and the clinical stage is T4N0M1c. Histological examination of the patient’s biopsy specimens revealed a Gleason score of 8 and a prostate-specific antigen level of 591.9 ng/ml before PET/MRI.