Metabolic Volumetric Parameters in ¹¹C-Choline PET/MR Are Superior PET Imaging Biomarkers for Primary High-Risk Prostate Cancer

Table 2

Correlation matrix of imaging biomarkers and clinical parameters.

		SUVmax	SUVmean	UVP	MTV	Ktransmax	Ktranskur	Kepmax	Kepkur	iAUCmax	iAUCkur	ADCmin	ADCmean	ADCkur	PSA	GS
SUVmax	Correlation	1	0.90	0.69	0.59	0.35	0.15	0.18	−0.04	0.40	0.25	−0.04	−0.19	0.10	0.46	−0.31
	value		<0.01	<0.01	<0.01	0.06	0.41	0.35	0.85	0.03	0.18	0.82	0.31	0.60	0.01	0.10
SUVmean	Correlation		1	0.56	0.42	0.19	0.06	−0.02	−0.19	0.28	0.25	0.09	−0.30	0.14	0.39	−0.33
	value			<0.01	0.02	0.30	0.76	0.92	0.31	0.13	0.17	0.64	0.10	0.47	0.03	0.07
UVP	Correlation			1	0.98	0.37	0.31	0.34	0.30	0.51	0.45	−0.41	−0.31	0.37	0.76	0.16
	value				<0.01	0.04	0.09	0.06	0.11	<0.01	0.01	0.02	0.09	0.04	<0.01	0.40
MTV	Correlation				1	0.39	0.25	0.41	0.40	0.51	0.48	−0.47	−0.28	0.40	0.75	0.25
	value					0.03	0.17	0.02	0.03	<0.01	0.01	0.01	0.12	0.03	<0.01	0.18
Ktransmax	Correlation					1	1	0.80	0.55	0.60	0.47	−0.24	0.02	0.37	0.18	0.04
	value						<0.01	<0.01	<0.01	<0.01	0.01	0.20	0.93	0.04	0.34	0.83
Ktranskur	Correlation						1	0.74	0.71	0.34	0.78	0.01	−0.09	0.30	0.10	0.25
	value							<0.01	<0.01	0.07	<0.01	0.95	0.64	0.10	0.58	0.17
Kepmax	Correlation							1	0.80	0.50	0.47	−0.31	−0.04	0.21	0.15	0.21
	value								0.00	0.00	0.01	0.09	0.84	0.26	0.41	0.25
Kepkur	Correlation								1	0.32	0.47	−0.26	−0.11	0.24	0.20	0.41
	value									0.09	0.01	0.15	0.57	0.19	0.29	0.02
iAUCmax	Correlation									1	0.36	−0.25	−0.01	0.26	0.30	0.11
	value										0.046	0.17	0.95	0.16	0.10	0.57
iAUCkur	Correlation										1	−0.08	−0.35	0.30	0.33	0.36
	value											0.68	0.05	0.10	0.07	0.049
ADCmin	Correlation											1	0.14	−0.08	−0.36	−0.33
	value												0.44	0.66	0.046	0.07
ADCmean	Correlation												1	−0.20	−0.38	−0.22
	value													0.28	0.04	0.23
ADCkur	Correlation													1	0.23	0.35
	value														0.22	0.06
PSA	Correlation														1	0.17
	value															0.35
GS	Correlation															1
	value

Statistically significant by Spearman’s correlation method. PSA, prostate-specific antigen; GS, Gleason score.