Research Article

Positron Emission Tomography Imaging of Macrophages in Atherosclerosis with 18F-GE-180, a Radiotracer for Translocator Protein (TSPO)

Table 1

Characteristics of studied animals.

LDLR–/–ApoB100/100C57BL/6NLDLR–/–ApoB100/100, block

Number of mice663
Weight (g)39.5 ± 6.234.6 ± 3.630.9 ± 6.3
Age (months)6.8 ± 0.35.7 ± 0.57.0 ± 0.2
High-fat diet (months)4.6 ± 0.15.0 ± 0.2
Injected radioactivity (MBq)10.0 ± 0.210.1 ± 0.510.3 ± 0.2

The data are given in mean ± standard deviation. Block: excess amount of nonradioactive GE-180 given intravenously 5 minutes before administration of 18F-GE-180.