Manganese-Enhanced T₁ Mapping in the Myocardium of Normal and Infarcted Hearts

Figure 5

DEMRI versus MEMRI vs MTC. (a) Comparison of magnetic resonance imaging and histological quantification of infarct size. Infarct size as a percentage of left ventricular myocardium at maximal infarct short-axis slice by DEMRI and MEMRI T₁ mapping and histologically with MTC. Note the inverted T₁ colour map configuration between DEMRI T₁ mapping and MEMRI T₁ mapping, calibrated to define infarct (pink) and remote (green) myocardium with intermediate values (yellow). (b) Bland–Altman plots showing differences between DEMRI inversion recovery (A), DEMRI T₁ mapping (B), and MEMRI T₁ mapping (C) for each rat heart. The average difference (bias) between the measurements is shown (dashed lines) ±2 × SD (dotted lines) for all three modalities.

(a)

(b)