MR Imaging-Histology Correlation by Tailored 3D-Printed Slicer in Oncological Assessment

Figure 2

(a) Breast lesion detection and outline; (b) 3D lesion segmentation and slicer design; (c) lesion modeling and slicer prototyping; (d) lesion surgical excision with directional markers; (e) thick lesion slicing according to MR protocol; (f) thin slicing for histological assessment (blue arrow); (g) histological staining and immunohistochemistry; (h) structural, diffusion, and perfusion maps (represented in pseudocolor) corresponding to histological section.